Transfer Airline Ticket From One Person To Another

Can an airline ticket be transferred from one person to another due to the first person not being able to make the flights? The flight #417 departs DTW Mar. 6 @6.20 am. to Fort Lauderdale. Flight #201 departs Fort Lauderdale 2:49 pm to St. Thomas. The return flight #212 departs St. Thomas Mar. 13 @4:08 pm to Fort Lauderdale. Flight #380 from Fort Lauderdale to DTW @8:20 pm. If this can be done, what is the charge and how do we go about changing the ticket from one person to another. Thank you.